<Grid>

        <DataGrid Name="datagrid1" Margin="148,68,0,0" AutoGenerateColumns="False" Height="131" Width="244">

            <DataGrid.Columns>

                <DataGridTextColumn Header="科室" Width="105" Binding="{Binding Path=Name}" />

                <DataGridTextColumn Header="人数" Binding="{Binding Path=Number}" />

                <DataGridComboBoxColumn ItemsSource="{Binding Path=People}" SelectedItemBinding="{Binding Path=K_科长}" 

Header="科长" />

            </DataGrid.Columns>

        </DataGrid>       

    </Grid>

public partial class MainWindow : Window

{

    public MainWindow()

    {

        InitializeComponent();

        ObservableCollection<Company> obc = new ObservableCollection<Company>();

        obc.Add(new Company() { Name = "人教科",Number=2,K_科长="熊俊",People=new List<string>(){"熊俊","王晓"}});

        obc.Add(new Company() { Name = "广告科", Number = 2, K_科长 = "汤姆", People = new List<string>() { "汤姆", "杰克" } });

        obc.Add(new Company() { Name = "财会科", Number = 2, K_科长 = "李莹", People = new List<string>() { "李莹", "张三" } });

        obc.Add(new Company() { Name = "人教科", Number = 4, K_科长 = "李刚", People = new List<string>() { "李刚", "王二","牛熊","刘麻子" } });

        datagrid1.ItemsSource = obc;

    }

}

class Company

{

    public string Name { get; set; }

    public int Number { get; set; }